JangaFX is developing a real-time volumetric fluid simulation tool called EmberGen. The developers state that it can “instantly simulate, render, and export flipbooks/sprite sheets to any game engine.”
EmberGen aims to be intuitive and user-friendly with a node-based UI and several examples included to assist new users. Currently, EmberGen exports sprite sheets or flipbooks, but volumetric data export will be supported in the future.
The software is not yet publicly available, but interested users can sign up for an early access preview.